Dr. Diane Gregory
Associate Professor, Kinesiology & Physical Education and Health Sciences
Contact InformationEmail: email@example.com
Phone: 519-884-1970 ext.4582
Office Location: Bricker Academic Building, BA438
Postdoctoral Fellowship – Orthopaedic Surgery, University of California San Diego
PhD – University of Waterloo (2009)
MSc – University of Waterloo (2005)
BSc – University of Guelph (2003)
My research is in the area of biomechanics; specifically musculoskeletal spine health and the development of low back pain. Of particular interest is the intervertebral disc; the soft tissue found between each of the vertebrae. These discs can become injured as a result of trauma, or gradually as a result of overuse, and the way in which they become damaged changes as we age. My main interests lie in understanding disc herniation and disc degeneration. Disc herniation is often referred to as a “slipped disc”, “budging disc” and even “sciatica”. Degeneration, on the other hand, is a natural progressive breakdown of the disc that can occur simply with age. Clinically, these two injuries can result in significant low back pain due to abnormal tissue loading and potential nerve impingement. My research utilizes both a tissue-based (in vitro) approach as well as a human-based (in vivo) approach.
Specific research questions include:
1) How does the spine become injured?
2) What specific things do we do that increase our risk?
3) How can we prevent or rehabilitate these injuries?
Gregory, DE, Callaghan, JP. Examining the effect of prolonged vibration exposure on the tensile material properties of single layers of the annulus fibrosus. In press, Medical Engineering and Physics.
Brown, SHM, Gregory, DE, Carr, JA, Ward, SR, Masuda, K, Lieber, RL. ISSLS prize winner: Adaptations to the multifidus muscle in response to experimentally induced intervertebral disc degeneration. In press, Spine.
Milosavljevic, S, Gregory, DE, Pal, P, Carman, AB, Milburn, PD, Callaghan, JP. The interaction between skill, postures, forces and back pain in wool handling. Applied Ergonomics 42(6), 801-806. 2011.
Gregory, DE, Callaghan, JP. Does vibration influence the initiation of intervertebral disc herniation? An in-vitro analysis to determine a causal relationship. Spine 36(4), E225-236. 2011.
Gregory, DE, Veldhuis, JH, Horst, C, Brodland, GW, Callaghan, JP. Novel lap test determines the mechanics of delamination between annular lamellae of the intervertebral disc. Journal of Biomechanics 44, 97-102. 2011.
Gregory, DE, Callaghan, JP. A comparison of uniaxial and biaxial mechanical properties of the annulus fibrosus: A porcine model. Journal of Biomechanical Engineering 133(2), 024503. 2011.
Gregory, DE, Callaghan, JP. The dependence of strain rate on the material properties of the annulus fibrosus. Journal of Biomechanical Engineering 132(9), 091010. 2010.
Callaghan, JP, Gregory, DE, Durkin, JL. Do NIRS measures relate to subjective discomfort during sedentary tasks? International Journal of Industrial Ergonomics 40(2), 165-170. 2010. - Invited Paper
Pal, P, Milosavljevic, S, Gregory, DE, Carman, AB, Callaghan, JP. The influence of skill and low back pain on trunk postures and low back loads of shearers. Ergonomics 53(1), 65-73. 2010.
Gregory, DE, Laughton, C, Carman, A, Milosavljevic, S, Callaghan, JP. Trunk postures and peak and cumulative low back kinetics during upright posture sheep shearing. Ergonomics 52(12), 1576-1583. 2009.
Gregory, DE, Pal, P, Carman, A, Milosavljevic, S, Callaghan, JP. An Examination of Shoulder Postures and Moments of Force Among Different Skill Levels in the Wool Harvesting Industry. International Journal of Occupational Safety and Ergonomics 15(4), 347-356. 2009.
Gregory, DE, Brown, SHM, Callaghan, JP. Trunk muscle responses to suddenly applied loads: do individuals who develop discomfort during prolonged standing respond differently? Journal of Electromyography and Kinesiology 18, 495-502. 2008.
Gregory, DE, Callaghan, JP. Prolonged standing as a precursor for the development of low back discomfort: An investigation of possible mechanisms. Gait and Posture 23, 86-92. 2008.
Gregory, DE, Narula, S, Howarth, SJ, Russell, C, Callaghan, JP. The effect of cardiovascular fatigue on trunk muscle activation patterns and spine postures during simulated fire fighting tasks. Ergonomics 51, 1032-1041. 2008.
Gregory, DE, Milosavljevic, S, Callaghan, JP. An examination of shoulder kinematics and kinetics when using a commercial trunk harness while sheep shearing. Applied Ergonomics 39(1), 29-35. 2008.
Pal, P, Gregory, DE, Milosavljevic, S, Carmen, AB, Callaghan, JP. A literature review of low back injury risk in sheep shearing. Journal of Occupational Health and Safety: Australia and New Zealand, 24(5), 435-453. 2008.
Brown, SHM, Gregory, DE, McGill, SM. Vertebral end-plate fractures as a result of high rate pressure loading in the nucleus of the young porcine spine. Journal of Biomechanics 41(1), 122-127. 2008.
Nelson-Wong, E, Gregory, DE, Winter, DA, Callaghan, JP. Gluteus medius muscle activation patterns as a predictor of low back discomfort. Clinical Biomechanics 23, 545-553. 2008.
Gregory, DE, Milosavljevic, S, Callaghan, JP. Quantifying low back peak and cumulative loads in open and senior sheep shearers in New Zealand: Examining the effects of a trunk harness. Ergonomics 49(10), 968-981. 2006.
Gregory, DE, Dunk, NM, Callaghan, JP. The comparison of muscle activation and lumbar spine posture during prolonged sitting on a stability ball and in an office chair. Human Factors 48(1), 142-153. 2006.
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