Dr. Joel Weadge
Associate Professor, Biology & Chemistry
Contact InformationEmail: email@example.com
Phone: 519-884-0710 ext.2161 | lab ext.3022
Office Location: BA416 | Lab Location: SR411
Postdoctoral Training: · Molecular Structure and Function, The Hospital for Sick Children, Toronto (2008-2011) · Enzymology, Carlsberg Laboratory, Copenhagen (2007-2008)
PhD: · Microbiology, University of Guelph (2006)
BSc: · Honours Microbiology, University of Guelph (2000)
My interest in microbiology started during my undergraduate years at the University of Guelph. During my second year I was fortunate to begin working in the lab of Dr. Anthony Clarke who expanded my interest in microbiology to the fascinating world of protein biochemistry. While enrolled as a Ph.D. student in his lab, I focused on the functional characterization of carbohydrate-active enzymes involved in the O-acetylation of Neisseria gonorrhoeae peptidoglycan. I thoroughly enjoyed my time as a graduate student and looked to expand on this growing interest in enzymology and glycobiology by becoming a post-doctoral fellow at the Carlsberg Research Centre in Copenhagen in the lab of Dr. Monica Palcic. This was a fantastic opportunity as it allowed me to explore intense research within a completely new cultural setting. The research here involved the molecular characterization of human blood-group glycosyltransferases and broadened my scientific curiosity into the realm of structural biology. Upon returning to Canada, I was fortunate to have the opportunity to continue protein structure-function research in Dr. P. Lynne Howell’s lab (The Hospital for Sick Children in Toronto) where I was involved in the detailed characterization of the proteins responsible for the production of the exopolysaccharide, alginate, from Pseudomonas aeruginosa. This work was invaluable as it sparked my interest in biofilm-relevant polysaccharides that led to my current research involving bacterial cellulose production from various Enterobacteriaceae. Through all of these diverse research experiences, I have developed a multidisciplinary approach to tackling relevant research problems by employing biochemical, structural, microbiological and molecular biological techniques.
Research Program: Microbial glycobiology: Structure-function analysis of proteins that synthesize and export bacterial cellulose. (see the Research section for more details)
The Weadge Lab: To see current lab members and possible research opportunities click here.